Medicinal and Botanical Manufacturing — Business Survival Rate

An estimated 64% of medicinal and botanical manufacturing businesses survive their first 5 years, based on U.S. Census Bureau Business Dynamics Statistics. The annual business closure rate is 8.6%.

64%
5-Year Survival Rate
+1.4%
Net Growth Rate
2,086
Total Firms
198
Annual Firm Deaths

Is Medicinal and Botanical Manufacturing a Good Business to Start?

With a 64% five-year survival rate, medicinal and botanical manufacturing has an above-average survival rate compared to the national average of roughly 50%. This makes it a relatively safe industry to enter — businesses here tend to find stable demand and sustainable economics.

The annual exit rate of 8.6% is lower than many sectors, suggesting that once established, these businesses have staying power. That said, lower failure rates often correlate with higher barriers to entry or established competition.

Entry vs. Exit Rates

Annual rate of new businesses opening versus existing businesses closing.

Entry Rate (new businesses)10.6%
Exit Rate (closures)8.6%

Net positive: more businesses opening than closing (+2.1 pp spread).

Job Creation & Destruction

12.1%
Job Creation Rate
10.7%
Job Destruction Rate
+1.4%
Net Job Growth

The industry is adding jobs faster than losing them — a positive sign for both workers and new business owners looking to hire. Total employment: 322,925 workers across 2,086 firms.

Want to know how much medicinal and botanical manufacturing businesses actually make?

See full revenue benchmarks for Medicinal and Botanical Manufacturing

Frequently Asked Questions

What percentage of medicinal and botanical manufacturing businesses fail?
Approximately 36% of medicinal and botanical manufacturing businesses fail within their first 5 years. The annual closure rate is 8.6%, with 198 firms closing permanently in 2023.
Is the medicinal and botanical manufacturing industry growing or shrinking?
The medicinal and botanical manufacturing industry is currently stable with a net job creation rate of +1.4% per year. New businesses are entering at 10.6% while 8.6% close annually.

Source: U.S. Census Bureau, Business Dynamics Statistics (2023). Survival rate estimated from annual exit rates.